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High quality Exemestan powder CAS:107868-30-4

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Price : USD 20



Product Name: Exemestan 
Other name: 6-Methylenandrosta-1, 4-diene-3, 17-dione; 10, 13-Dimethyl-6-methylidene-7, 8, 9, 10, 11, 12, 13, 14, 15, 16-decahydrocyclopenta[a]phenanthrene-
MF: C20H24O2
MW: 296.4034
CAS: 107868-30-4
Appearance: White crystalline powder
Purity: 99%
Packing: sample 10g,100g500g,1kg
Storage: Shading, confined preservation

The hormone status of steroid users is very important, and the correct balance between androgen and estrogen plays an important role. Aromatization is a biochemical process that occurs in various tissues, such as breast, adipose tissue, liver and brain; Induced by aromatase, testosterone is converted to estradiol (E2).

In order to prevent the side effects of aromatization (water retention and fat storage), we usually use selective estrogen receptor modulators (SERMs) or more effective aromatase inhibitors (AIS). SERMs (tamoxifen, clomiphene) occupy the estrogen receptor locally, so that the circulating estrogen cannot adhere to the receptor. AI inhibits the production of estrogen by inhibiting the action of aromatase, which converts androgen into estrogen. Two types of AI include suicide steroid inhibitors such as exemestane and non steroidal inhibitors such as anastrozole and letrozole. Exemestane can prevent the rise of estradiol (E2) for a period of time after use, so as to prevent any rebound effect. The drug can almost inhibit the plasma and tissue estrogen level of total estrogen (estradiol-e2) by 85%. Occasionally, synthetic forms of dihydroxytestosterone / DHT (testosterone and drosterone) are also used to enhance the anti estrogen effect.

Nevertheless, estrogen does play an important role in muscle development. Estrogen makes androgen receptors more receptive to anabolic molecules. The study showed that scientists castrated male guinea pigs and then gave them the powerful anabolic steroid 17 alkylated drug methyltrienone (M3). With castration, mice significantly increased estrogen levels and eliminated their androgens. It was observed that the connection between m3 and the receptor was 500% stronger than that before castration. This explains how important estrogen is for the attachment of steroid molecules to the receptor surface.

Insulin like growth factor (IGF1) is a peptide responsible for muscle development and cartilage regeneration. It is well known that estradiol (E2) is present in the factors released by GH. With the decrease of estrogen, the concentration of growth regulator decreased. Aromatization is a process that promotes the existence of IGF1 peptide.

Exemestic is a very powerful and effective suicidal steroid aromatase inhibitor. The information contained in the Dutch act package describes the ability of the vagin to reduce estrogen level by 85%.

The bactericidal aromatase inhibitor exemestane can permanently inhibit the aromatase bound to it, which makes the enzyme inactive forever. The body will eventually produce more aromatase, but the currently bound enzymes bind indefinitely, eliminating any risk that estrogen will rebound. This is not related to the other two main aromatase inhibitors (anastrozole and letrozole), which are non suicidal aromatase inhibitors that bind to aromatase only for a limited time before aromatase inhibitor debinding and metabolism. If the non suicidal aromatase inhibitor suddenly stops, the aromatase that has not been metabolized out of cardiopulmonary bypass will be released again and begin to turn androgen into estrogen at an extremely fast rate. This is not the case with yimeitan.

Studies have shown that exemestane can increase the level of endogenous natural testosterone in men by 60%, which is quite significant, especially after only 10 days. That's why some people included it during PCT. Like letrozole, exemestane stimulates the pituitary to release more luteinizing hormone (LH) and follicle stimulating hormone (FSH), which are essential for natural testosterone production. And exemestane has been shown to have a slight androgen effect and the ability to increase the production of insulin-like growth factor-1 (IGF-1). This is beyond the reach of other anti female drugs. By using exemestane during PCT, individuals received an increase in the required testosterone for recovery, but also produced a stronger anabolic atmosphere with the increase of IGF-1. This is useful for steroid users because it can better protect their lean tissue during use.

Exemestane is an aromatase inhibitor. Its structure and function are similar to formestane, but the effect is much stronger. Aromatase inhibitors usually isolate aromatase to prevent the production of estrogen. Bodybuilders who use aromatized steroids usually use it to inhibit the side effects of feminization. Such side effects include bitch's milk, increased fat and water storage reactions. Sometimes aromatase inhibitors can also be used to reduce fat and improve muscle separation. Exemestane is one of the most powerful aromatase inhibitors available. The most recognized clinical trials in women show that exemestane has an anti estrogen efficiency of 85%

Exemestanne acetate Function:
Aromasin (Exemestanne acetate) is one of those weird compounds that nobody really knows what to do with. It's a third generation Aromatase Inhibitor (AI) just like Arimidex () and Femera.
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
1. Aromasin is one of the most powerful estrogen suppressing compounds.
2. Aromasin is one of the best compounds to lower the aromatizing effect of steroids.
3. Aromasin is available for body builders taking anabolic steroids.
4.It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.
5.Aromasin is also a kind of .antineoplastic (hormonal) raw materials.
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  • Place of Origin : China
  • FOB Price : USD 20
  • Minimum Order Quantity : 10g
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    Company profile: Wuhan Demeikai Biotechnology Co., Ltd. is a company engaged in the research and development and production of chemical raw materials. There are dozens of high-end technical researchers in professional laboratories to meet the needs of customers for various customized products; standardized production workshops, strict The quality control system guarantees that each batch of goods meets the company's quality standards and meets the quality requirements of customers; experienced sales staff are at your service at any time and solve various problems in the entire sales process for you; professional logistics channels guarantee international The safety of transportation, do my best to ensure that customers can safely receive your goods.
        
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 sample 10g,100g500g,1kg